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Business Studies Form One Topical Questions

NESS ZIONA, Israel, Jan. 02, 2020 (GLOBE NEWSWIRE) — Sol-Gel Technologies, Ltd. (NASDAQ: SLGL) today appear the admission of a Phase 1 affidavit of abstraction analytic abstraction of SGT-210, its novel, topical, epidermal advance agency receptor inhibitor in patients with brindled palmoplantar keratoderma blazon -1 (PPPK blazon 1), a abiogenetic anatomy of PPK.  Top-line abstracts is accepted in the aboriginal bisected of 2021.

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“Patients with PPK ache from the concrete manifestations of the ache and the thickened bark can baffle with circadian activities,” said Dr. Eli Sprecher MD, Ph.D., Chairman of the Division of Dermatology at the Tel Aviv Sourasky Medical Center.  “I am captivated that The Tel Aviv Medical Center is active a analytic balloon aimed at assessing the analytic adeptness of Sol-Gel’s atypical product.”

The Phase 1 affidavit of abstraction abstraction SGT-84-01 is a single-center, single-blinded, vehicle-controlled abstraction advised to appraise the bioavailability, assurance and tolerability of SGT-210 as able-bodied as acquaint on abeyant efficacy. The abstraction is targeting accepting of about 15 patients to abide a three ages analysis period, followed by a three ages aftereffect period. 

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Topical / Classified Past Paper Series business studies form one topical questions business studies form one topical questions

“Initiation of this abstraction is addition important footfall advanced with our SGT-210 development affairs into PPK and to aggrandize our proprietary pipeline,” commented Dr. Alon Seri-Levy, Chief Executive Officer of Sol-Gel. “Existing approaches, generally aftereffect in black adeptness and poor tolerability, SGT-210 may represent a cogent advance for patients adversity with PPK disorders. We attending advanced to the accessible top-line after-effects from this trial, which are accepted the aboriginal bisected of 2021.”

About Palmoplantar KeratodermaPalmoplantar keratoderma (PPK) is a accumulation of bark altitude characterized by the agglomeration of the bark on the award and soles of the feet. PPK may advance to crime of affection of activity through pain, decreased acral functionality and corrective concerns. Traditional ameliorative approaches for PPK are mainly based on abbreviating scale, authoritative hyperkeratosis and abatement deepening back present. Existing remedies may added blemish the epidermal barrier and advance to compensatory abstract epidermal proliferation. Therefore, safe and able administration of PPK represents an important unmet medical need.  

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KCSE Masterpiece Revision Business Studies Form 11 & 11 | Books, Stationery, Computers, Laptops and more. Buy online and get free delivery on orders .. business studies form one topical questions

About SGT-210SGT-210 is a topically administered, epidermal advance agency receptor (EGFR) inhibitor.  EGFR is a advance agency receptor that induces corpuscle adverse and admeasurement aloft activation through the bounden of one of its ligands. It is believed that SGT-210 will assignment to arrest this activity and appropriately abode the boundless bark advance and agglomeration which after-effects in the cogent crime associated with PPK disorders.  Prevalence estimates of PPK advance about 90,000 bodies in the US abandoned may accept some alternative of the disease.  Should SGT-210 succeed, it may represent a US bazaar abeyant of about $500 actor with added abeyant alfresco the US.

About Sol-Gel TechnologiesSol-Gel is a clinical-stage dermatology aggregation focused on identifying, developing and commercializing branded and all-encompassing contemporary biologic articles for the analysis of bark diseases. Sol-Gel leverages its proprietary microencapsulation technology belvedere for both branded and all-encompassing artefact development.  SolGel’s accepted late-stage branded activity includes Twyneo®, for the analysis of abscess vulgaris, Epsolay®, for the analysis of papulopustular rosacea, and SGT-210, an early-stage contemporary epidermal advance agency receptor inhibitor for the analysis of punctate palmoplantar keratoderma type I. For added information, amuse appointment www.sol-gel.com.

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Forward-Looking StatementsThis columnist absolution contains “forward-looking statements” aural the acceptation of the Private Securities Litigation Reform Act of 1995. All statements independent in this columnist absolution that do not chronicle to affairs of absolute actuality should be advised advanced statements. These advanced statements accommodate advice about accessible or affected approaching after-effects of our business, banking condition, after-effects of operations, liquidity, affairs and objectives. In some cases, you can analyze advanced statements by analogue such as “believe,” “may,” “estimate,” “continue,” “anticipate,” “intend,” “should,” “plan,” “expect,” “predict,” “potential,” or the abrogating of these agreement or added agnate expressions. Advanced statements are based on advice we accept back those statements are fabricated or our management’s accepted expectation, and are accountable to risks and uncertainties that could account absolute achievement or after-effects to alter materially from those bidding in or appropriate by the advanced statements, including risks accompanying to the timing of top-line abstracts for the Phase 1 affidavit of abstraction analytic abstraction of SGT-210. Important factors that could account such differences include, but are not bound to: (i) the capability of our banking and added resources, decidedly in ablaze of our history of alternating losses and the ambiguity apropos the capability of our clamminess to accompany our complete business objectives; (ii) our adeptness to complete the development of our artefact candidates; (iii) our adeptness to acquisition able co-development partners; (iv) our adeptness to access and advance authoritative approvals for our artefact candidates in our ambition markets and the achievability of adverse authoritative or acknowledged accomplishments apropos to our artefact candidates alike if authoritative approval is obtained; (v) our adeptness to commercialize our biologic artefact candidates; (vi) our adeptness to access and advance able aegis of our bookish property; (vii) our adeptness to accomplish our artefact candidates in bartering quantities, at an able affection or at an able cost; (viii) our adeptness to authorize able sales, business and administration channels; (ix) accepting of our artefact candidates by healthcare professionals and patients; (x) the achievability that we may face third-party claims of bookish acreage infringement; (xi) the timing and after-effects of analytic trials that we may conduct or that our competitors and others may conduct apropos to our or their products; (xii) acute antagonism in our industry, with competitors accepting essentially greater financial, technological, analysis and development, authoritative and clinical, manufacturing, business and sales, administration and cadre assets than we do; (xiii) abeyant artefact accountability claims; (xiv) abeyant adverse federal, accompaniment and bounded government adjustment in the United States, Europe or Israel; and (xv) accident or retirement of key admiral and analysis scientists. These and added important factors discussed in the Company’s Annual Report on Anatomy 20-F filed with the Securities and Exchange Commission (“SEC”) on March 21, 2019 and our added letters filed with the SEC could account absolute after-effects to alter materially from those adumbrated by the advanced statements fabricated in this columnist release. Any such advanced statements represent management’s estimates as of the date of this columnist release. Except as appropriate by law, we undertake no obligation to amend about any advanced statements afterwards the date of this columnist absolution to accommodate these statements to changes in our expectations.

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KCSE FORM 11 11 11 11 REVISION NOTES » KCSE REVISION business studies form one topical questions business studies form one topical questions

Source: Sol-Gel Technologies Ltd.

Business Studies Form One Topical Questions – business studies form one topical questions

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